Research Article

Synthesis of α-ribonucleoside (Majority) by the Coupling of NP/KI and NP/I₂

Driss Ouzebla
Université Cadi-Ayyad, Morocco
* Corresponding author
DOI icon 10.24018/ejchem.2020.1.6.30

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Submitted 2020-11-23
Published 2020-12-03

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Article Main Content

In this work we will demonstrate a method of preparing α-D-ribonucleosides using the solid-phase approach using the combination between natural phosphate doped with potassium iodide (NP/KI) and natural phosphate doped with iodine (NP/I2). All these derivatives ribonucleosides were prepared by N-glycosylation reaction between silylated bases and 1-O-acétyl-2,3,5-tri-O-benzoyl-β-D-ribofuranoside.

Keywords: α-ribonucleosides NP/KI NP/I₂ Reflux

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